Hairy cell leukemia remission
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Cytarabine Idarubicin (7 3 regimen 1)Cytarabine (Ara-C) 100 mg/m2/d civi d1-7Idarubicin 12 mg/m2/d iv d1-3Wiernik PH et al. change ECGs to watercraft QTc at baseline, 7 days after initiation, and periodically thereafter, as well as following dose adjustments Approved by FDA on 10/29/07 (link to the FDA file). Failure to achieve a major genetics reply by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for degenerative myeloid leukemia. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukemia (the LRF CLL4 trial): a randomised controlled trial. Fludarabine Rituximab Fludarabine 25 mg/m2/d iv d1-5Rituximab (Rituxan) 375 mg/m2 iv d1 and 4 of repeat 1, then d1 single for cycles 2-6Q4w x 6 cycles2 months later: Rituximab (Rituxan) 375 mg/m2 iv qw x 4 doses explorer JC et al. Addition of rituximab to fludarabine may prolong progression-free survival and boilers suit natural selection in patients with antecedently untreated chronic white blood corpuscle leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Fludarabine Cyclophosphamide Rituximab (FCR)Fludarabine 25 mg/m2/d iv d1-3Cyclophosphamide (Cytoxan) 250 mg/m2/d iv d1-3Rituximab (Rituxan) 375 mg/m2 iv d1 round 1 and 500 mg/m2 iv d1 cycle 2-6Q4w x 6 cycles Allopurinol 300 mg po qd d1-7 cycle 1 Bactrim DS 1 po bid twice a week Valacyclovir 500 mg po qd Tam CS et al. Cladribine alone and in combination with cyclophosphamide or cyclophosphamide advantageous mitoxantrone in the aid of progressive chronic lymphocytic leukemia: account of a prospective, multicenter, randomized trial of the glossiness Adult Leukemia mathematical group (PALG CLL2). CVPCyclophosphamide (Cytoxan) 300 mg/m2/d po d1-5Vincristine 1.4 mg/m2 (max 2 mg) iv d1Prednisone 100 mg/m2/d po d1-5Q3w up to 18 months archangel B et al. Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia. Cytarabine Daunorubicin (7 3 regimen 2)Cytarabine (Ara-C) 100 mg/m2/d civi d1-7Daunorubicin 45-60 mg/m2/d iv d1-3Wiernik PH et al. Comparison of three remission induction regimens and two postinduction strategies for the treatment of acute nonlymphocytic leukemia: a Cancer and Leukemia Group B study. Lestaurtinib (CEP701) (for old patients)60-80 mg po bid Knapper S et al. Dasatinib (SPRYCEL) 50 mg or 70 mg bid versus 100 mg or 140 mg qd in patients with chronic connective tissue leukemia in chronic phase (CML-CP) insusceptible or uncharitable to imatinib: results of the CA 180-034 study. Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in grounds untreated patients with B-cell chronic lymphocytic leukemia: results from Cancer and Leukemia class B9712. Seventy proportionality of complete responders remain in continuous remission: five-year follow-up of 300 patients treated with fludarabine, cyclophosphamide, and rituximab (FCR) as initial therapy of CLL. similitude of chlorambucil and prednisone versus cyclophosphamide, vincristine, and prednisone as initial treatment for chronic wbc leukemia: long-term follow-up of an east-central Cooperative medical speciality Group randomised clinical trial. Lenalidomide Regimen 1Lenalidomide (Revlimid) 5 mg po qd, step up by 5 mg every 1-2 weeks to 25 mg po qd d1-21 q4w until building block CR or unacceptable toxicity medication 300 mg po qd for 14 days play 2-3 days earlier lenalidomide Chanan-Khan A et al. Cytarabine positive idarubicin or daunorubicin as induction and consolidation medical care for previously unprocessed soul patients with perceptive myeloid leukemia. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for aged patients with penetrating myeloid leukemia not considered fit for intensive chemotherapy. Decitabine Valproic acid (for old patients)Decitabine 15 mg/m2 iv over 1 h qd d1-10Valproic virulent 50 mg/kg po qd d1-10Q4w Garcia-Manero G et al. Dasatinib (BMS-354825) is proactive in Philadelphia chromosome-positive habitual myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure. Clinical effectivity of lenalidomide in patients with relapsed or refractory confirmed lymphocytic leukemia: Results of a phase II study. Regimen 2Lenalidomide (Revlimid) 10 mg po qd for 28 days, and so increase by 5 mg all 28 days to 25 mg qd until advance or unacceptable definite quantity Ferrajoli A et al.
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Chemoregimen - Leukemia
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Blastic plasmacytoid dendritic cell neoplasm (BPDCN), previously acknowledged as uncoloured individual (NK) cell leukemia/lymphoma, is categorized by the World welfare Organization (4th edition, 2008) under acute myeloid leukemia (AML). Most often, BPDCN presents with features of both malignant neoplastic disease and leukemia. at that place are little accumulation about BPDCN and in that location is no established treatment. There are further men than women who are diagnosed with BPDCN.
Published: 06.03.2018 at 08:14
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